BackgroundTumour suppressor genes are often transcriptionally silenced by promoter hypermethylation. and recent research has implicated alterations in chromatin structure as the mechanistic basis for this repression. In addition to DNA methylation. other epigenetic post-translational modifications that modulate the stability and binding of specific transcription factors to gene promot... https://www.roneverhart.com/Dr-Squish-Squishy-Refill/