During human immunodeficiency virus-1 (HIV-1) assembly. the host proteins CD4 (the HIV-1 receptor) and tetherin (an interferon stimulated anti-viral protein) both reduce viral fitness. The HIV-1 accessory gene Vpu counteracts both of these proteins. but it is thought to do so through two distinct mechanisms. https://hollandscountryclothinges.shop/product-category/drying-mitts/